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June 21 2018 Meeting: “A Novel Therapeutic Strategy For The Metabolic Management Of Cancer” by Thomas Seyfried, PhD

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Main Presentation: “A Novel Therapeutic Strategy For The Metabolic Management Of Cancer” by Thomas Seyfried, PhD

A shift from respiration to fermentation is a common metabolic hallmark of cancer cells. As a result, glucose and glutamine become the prime fuels for driving the dysregulated growth of tumors. The simultaneous occurrence of “Press-Pulse” disturbances was considered the mechanism responsible for reduction of organic populations during prior evolutionary epochs. Press disturbances produce chronic stress, while pulse disturbances produce acute stress on populations. It was only when both disturbances coincide that population reduction occurred.

This general concept can be applied to the management of cancer by creating chronic metabolic stresses on tumor cell energy metabolism (press disturbance) that are coupled to a series of acute metabolic stressors that restrict glucose and glutamine availability while also  stimulating cancer-specific oxidative stress (pulse disturbances). The elevation of non-fermentable ketone bodies protect normal cells from energy stress while further enhancing energy stress in tumor cells that lack the metabolic flexibility to use ketones as an efficient energy source. Mitochondrial abnormalities and genetic mutations make tumor cells vulnerable metabolic stress.

 

About Thomas Seyfried, PhD

thumbnailThomas N. Seyfried is Professor of Biology at Boston College, and received his Ph.D. in Genetics and Biochemistry from the University of Illinois, Urbana, in 1976. He did his undergraduate work at the University of New England where he recently received the distinguished Alumni Achievement Award. He also holds a Master’s degree in Genetics from Illinois State University, Normal, IL. Thomas Seyfried served with distinction in the United States Army’s First Cavalry Division during the Vietnam War, and received numerous medals and commendations. He was a Postdoctoral Fellow in the Department of Neurology at the Yale University School of Medicine, and then served on the faculty as an Assistant Professor in Neurology.

Other awards and honors have come from such diverse organizations as the American Oil Chemists Society, the National Institutes of Health, The American Society for Neurochemistry, and the Ketogenic Diet Special Interest Group of the American Epilepsy Society. Dr. Seyfried previously served as Chair, Scientific Advisory Committee for the National Tay-Sachs and Allied Diseases Association.

He recently received a Lifetime Achievement Award from the Academy of Complimentary and Integrative Medicine, and the Uncompromising Science Award from the American College of Nutrition for his work on cancer for his work on cancer. He presently serves on several editorial boards, including those for Nutrition & Metabolism,  Neurochemical Research, the Journal of Lipid Research, and ASN Neuro.

Dr. Seyfried has over 180 peer-reviewed publications and is author of the book, Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer (Wiley Press). His full list of peer-reviewed publications can be found on PubMed.

 

Short Presentation: “Updates On Gut Microbiome In Health And Disease” by Christine Rosche, MPH, CNS, CBT

It will be presented a research overview that discusses the importance of testing and treatment interventions for best outcomes. Also how to determine the best viable probiotics strains with examples of case studies from her practice. The highlights will be on:

* Probiotics essential for nutrient absorbtion
* Functional testing for determining if you have a healthy microbiome
* Role of gut bacteria in the prevention and treatment of certain cancers
* The role of gut bacteria and permeability in neurodegeneration, Alzheimer’s diseas and dementia

About Christine Rosche, MPH, CNS, CBT

christine_roscheChristine Rosche, MPH, CNS, CBTis a Board Certified Nutrition Specialist and Biofeedback Therapist  with 25 years experience in the health care field.

She developed  and taught courses at  Stanford University Medical Center and Heart Disease Prevention Program and is the author of 2 books.

She has maintained a private practice in Palo Alto since 1980 and specializes in functional testing and integrative approaches for digestive issues including GERD, malabsorption issues, gut permeability, IBS, IBD, Crohns, constipation and inflammatory bowel disease.

As a licensed Heart Math™ Trainer, Christine is  pioneering the integration of  Heart Math ™ Heart Rate Variability (HRV) Biofeedback Training with Custom Nutrition and Gut Healing Protocols.

 

 

For more info, read the newsletter.

NOTE: Meeting starts promptly at 7pm.  Main speaker presentation begins at 7:20 p.m.

Join us! $10 at the door, or join as a Member to the right and get a 50% reduced admission price.

 

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